Identification and Biological Activities of the Phenolic Compounds in <i>Eisenia arborea</i>

Four polyphenols were isolated and purified from a brown alga Eisenia arborea. These phlorotannin compounds showed strong radical scavenging some enzyme inhibitory activities. All of the antioxidative, acetylcholinesterase butyrylcholinesterase inhibitory, tyrosinase inhbibitory activities at 100 μg/mL. Dieckol PFF inhibited butyrylcholinesterase, new target for treatment Alzheimer’s disease, very strongly even 10 μg/mL, more than AChE. two also effectively tyrosinase. results support potential developing natural antioxidants antidementia agents alga.